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高中少女渚凛（杉本有美 饰）即将迎来16岁的生日，但是她却发现自己的身体正悄悄发生着变化。生日当天，凛受到强烈刺激，右手变成了削铁如泥的魔爪。仓皇回到家中的她从父亲洋二郎（津田寛治 饰）口中得知，自己竟是变异人“蛭子”的族人。接着她眼睁睁看着父母被隶属于日本政府的特种部队杀害。愤怒的凛唤醒了身体内的魔性，在家乡附近的商业街大开杀戒。此后凛遇到蛭子一族的美男子首领如月（坂口拓 饰）和高中女生玲（高山侑子 饰），如月发誓建立一支足以与人类抗衡的战斗少女部队，而玲正是这群蛭子女孩的战斗教练。种族战争一触即发…… 本片分为三章，各由坂口拓、井口昇、西村喜廣三位导演执导。
The film opens in a bleak police station where celebrated war correspondent Kate Rafter (Seagrove) faces questions from a psychiatrist, Dr Shaw (Kurylenko), as they work through the painful events of Rafter’s life. A horrific incident in war-torn Iraq and the death of her mother (Steed) have brought a haunted Rafter home to Herne Bay, a place she believed she had escaped forever. Her resentful sister (Friel) has not made her sister welcome and her forbearing husband Paul (Miles) fails to broker peace. Whilst packing up her mother’s belongings from her childhood home, Rafter comes to believe there is something strange and terrifying happening in the house next door.
