故事讲述了杨家父女、张三链子等一行人，在军阀阎立本的胁迫下踏入神农架密林。在森林中先后遭遇各种生物攻击，危难之际众人被野人营救。阎立本因贪念最终被巨蜥杀死，野人为了保护神农架奋勇搏斗，最终几人合力将巨蜥击杀，深林和村落再次回归平静。
露丝·斯雷特（布洛克饰）因暴力犯罪被判入狱，出狱后的她重新踏入社会，但自己的过去却不被原谅。面对来自她曾经称之为“家”的地方的无情评判，她获得救赎的唯一希望，就是找到当初被自己无奈丢下而疏远了的妹妹。
At the dawn of the 20th century, Buffalo Bill’s Wild West Show rolls into Italy, peddling the myth of the American frontier and sparking the imagination of Rosa, a young woman trapped in a stifling marriage to a powerful and violent landowner. When a rodeo between American cowboys and Italian butteri ends in tragedy, Rosa flees with Santino, the daring local rider who bested the Americans. But in a world where justice is sold to the highest bidder, Buffalo Bill and others join the hunt for the bounty on Santino’s head. Rosa’s dream of freedom quickly collides with the weight of reality—and like in every good Western ballad, fate flips a coin.
