该剧讲述1948年至1980年发生在淮河岸边、念恩桥两岸的感人故事。剧中，刘涛饰演的男主角“耿长和”是解放军猛虎团红三连的连长，在战争年代，面对炸毁念恩桥的军事命令，却因考虑到两岸劳苦人民生息问题而拒绝服从上级安排，从而导致经历了一系列的艰难坎坷。
改编自爱奇艺小说作者初墨不姓熊《误杀记忆》。 六年前，因为一场车祸，苏软昏睡病床。六年后，她奇迹般苏醒。 回到家中的她意外发现了一本日记本，日记本确定是她的笔迹，时间是六年前。 日记本记录了一件关于她的秘密，她杀了人。 苏软对这部分的记忆全无，她患了心因性失忆症中的局部性失忆症，选择性遗忘了一些发生过的事， 她丧失地部分记忆，以日记这种特殊的方式储存了起来，然而因为日记本存放年久，后半部分受潮，字迹变得模糊不清无法辨认。 苏软不愿意相信自己杀了人，她身边多了一个又一个的陌生人，他们的目的，直指六年前废弃医院的凶杀案。 苏软不得不踏上了自证清白之路。
A rootless genius, Iris Nixon, steals an enigmatic code from a charming philanthropist and disappears. A tense countdown ensues as she races to unravel the code's mystery.
Season 5 finds Murder, She Wrote's intrepid Jessica Fletcher in fine sleuthing form, and venturing farther afield from Cabot Cove--a good thing, since at the rate the murders have been happening, that town would be nearly cleaned out. Some of the best episodes take place in more exotic locales like New York (dead man on the street, wearing just one shoe), Montana (a publishing convention gone horribly wrong) and West Virginia (two whistle-blowers at a coal company found gruesomely murdered). Angela Lansbury sparkles with determination and bonhomie, hitting her stride and then some. Jessica's own life backstory is even filled out tantalizingly, especially in the episode "The Last Flight of the Dixie Damsel," in which an investigation is launched into a mysterious cargo plane that is linked, she learns to her horror, to her late husband. The series' other delight is watching for cameos by stars of a certain age, and this season doesn't disappoint, with appearances by Roddy McDowall, Shelley Fabares, and Dinah Shore--but also some up-and-comers like Megan Mullally (proof positive that the Will & Grace whine was a put-on) and future satirist Bill Maher.
台湾联大医院外科主治医师苏怡华（言承旭 饰）年轻有为，善良的他希望能做一个好医生，心中只想着帮病人解脱疾病的折磨。老院长即将退休，外科主任唐国泰（吴孟达 饰）与内科医生徐大明都是接任的人选。面临升迁的大好机会，两人开始明争暗斗。 此时，台湾领导人的女儿刘心萍（Sanya 饰）患白血病入住了联大医院，院方高度重视。刘心萍也成为了内科与外科之间较量的主要对象，一场白色医袍下丑陋的尔虞我诈的人性角力正式开始…… 面对一系列的钩心斗角以外，苏怡华与外科副主任邱庆成（戴立忍 饰）也要面对剪不断理还乱的感情线，医生能医不自医。
驿站附近的乐活山庄，暗中收集情报。女掌柜田津津聪明机警，乐于助人，跑堂田大壮武功高强，琴师朴岛毅见多识广。账房田大娘眼力佳记性好。四人各有秘密，却凑到一起。意气风发的福将军因得罪权贵，被贬中枢驿站。但实际上是来中枢城查一件要案。二人日久生情之际，边关急信丢失，送信差役惨死，彻底搅动了城中风云
